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I was feeling so crappy before starting, I didn't want to take any chances GE. 803)] Most generic medications are more or less the same. If you search the orange book you can get more information Synthroid vs. With most medicines, it doesn’t matter if you take the generic or brand name version or if you switch between them Conclusions and relevance: Initiation of generic vs brand-name levothyroxine formulations was associated with similar rates of normal and stable thyrotropin levels. Comparative Effectiveness of Persistent Use of a Name-Brand Levothyroxine (Synthroid®) vs. She said this is one of the only drugs she really recommends not to take the generic. Publication types Comparative Study. There can be subtle differences from manufacturer to manufacturer in the actual dosage. As a generic, levothyroxine is significantly cheaper than Synthroid. Persistent Use of Generic Levothyroxine on TSH Goal Achievement: A Retrospective Study Among Patients with Hypothyroidism in a Managed Care Setting. I've also read that synthroid comes from one company while generics can come from a multitude of companies. She said she has seen some patients that don't absorb the generic as well. If Read More Created for people with ongoing healthcare needs but benefits everyone. Using a linear mixed model, children treated with the generic LT4 had lower TSH estimated SD [1. Brand name Synthroid and generic levothyroxine are chemically identical hormones, l-thyroxine. At least I have heard it several times Just today, I picked up what I thought was my Synthroid refill to find out it was generic, very upset, 90 days worth, can't return it, most likely …. Except with Levothyroxine/Synthroid. The inert ingredients vary, but that's trivial. Levothyroxine is also available under other brand names, including Tirosint® and Levoxyl® Brand vs. Generic Levothyroxine Ericamegan My endo recommended that I take Synthroid instead of the generic. Liothyronine, on the other hand, contains the most potent thyroid hormone which is known as T3 or triiodothyronine. Generic: What the Research Says According to a presentation at the annual meeting of the American Association of Clinical Endocrinologists in 2017, Synthroid was associated with significantly better thyroid-stimulating hormone (TSH) lab results than generic levothyroxine. I was prescribed generic levo but I know my mom (longtime hypo) made me go get synthroid prescribed the next week lol Most generic medications are more or less the same. 6k views Answered >2 years ago Thank 1 thank View 1 more answer A member asked:. These results suggest that generic levothyroxine as initial therapy for mild thyroid dysfunction is as effective as brand-name levothyroxine. 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